Devarim 22:9

כלאים [THOU SHALT NOT SOW THY VINEYARD] WITH DIVERSE KINDS OF SEEDS — i.e. wheat and barley together with kernels of grapes with one and the same hand-throw (Berachot 22a; Kiddushin 39a; Chullin 82b). פן תקדש LEST IT BECOME קדש — Take it as the Targum does: lest it become unclean (unfit for use); to anything for which a man has repugnance to come into contact with, be it on account of its sublimity as, for instance, holy things, or be it on account of some bad quality, as, for instance, something that is forbidden, the term קדוש is appropriate, as, in the latter sense, e.g., (Isaiah 65:5) “Come not near to me for I make thee קדוש". [המלאה — This is the fullness and increase which the seed produces].

לֹא־תִזְרַ֥ע כַּרְמְךָ֖ כִּלְאָ֑יִם פֶּן־תִּקְדַּ֗שׁ הַֽמְלֵאָ֤ה הַזֶּ֙רַע֙ אֲשֶׁ֣ר תִּזְרָ֔ע וּתְבוּאַ֖ת הַכָּֽרֶם׃ {ס}        

Thou shalt not sow thy vineyard with divers seeds: lest the fruit of the seed which thou hast sown, and the fruit of the vineyard, be forfeited.